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URL consultato il 12 novembre 2012. © 2018 Zajo. 2017: cronaca di un anno Tim'rous Beastie SERIE SPECIALI Denver, CO BLOG Stiamo collaborando con i pescatori per rimuovere la plastica dall’oceano. La plastica viene poi riciclata sotto forma di filato e utilizzata per realizzare le nostre nuovissime camicie con Tech Prep™. 30  Handcrafted, Wood-Fired, Neapolitan Pizza and Italian Shared Plates Glycerol-3-phosphate acyltransferases (GPAT) catalyze the first and rate-limiting step in the de novo glycerolipid synthesis. The GPAT2 isoform differs from the other isoforms because its expression is restricted to male germ cells and cancer cells. It has been recently reported that GPAT2 expression in mouse testis fluctuates during sexual maturation and that it is regulated by epigenetic mechanisms in combination with vitamin A derivatives. Despite progress made in this field, information about GPAT2 role in the developing male germ cells remains unclear. The aim of this study was to confirm the hypothesis that GPAT2 is required for the normal physiology of testes and male germ cell maturation. The gene was silenced in vivo by inoculating lentiviral particles carrying the sequence of a short-hair-pin RNA targeting Gpat2 mRNA into mouse testis. Histological and gene expression analysis showed impaired spermatogenesis and arrest at the pachytene stage. Defects in reproductive fitness were also observed, and the analysis of apoptosis-related gene expression demonstrated the activation of apoptosis in Gpat2-silenced germ cells. These findings indicate that GPAT2 protein is necessary for the normal development of male gonocytes, and that its absence triggers apoptotic mechanisms, thereby decreasing the number of dividing germ cells. 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Bambolina Photo Gallery TK (29) +EUR 14,00 di spedizione (Change country) For the Pro Digital Educational Reset 10/5/2017 Per alcune donne il reggiseno è un simbolo delle limitazioni che la società impone alle donne: "Il classico atto di bruciare il reggiseno … rappresentava la liberazione dall'oppressione del patriarcato maschile, fino a scioglierti dalle costrizioni necessarie per avere una silhouette dolce."[104] Questa affermazione era in sintonia con le tante donne che avevano messo in discussione il proprio ruolo nella società e lo status femminile confrontato con il maschile. Si stabilì un nesso del femminismo con il cosiddetto movimento "brucia il reggiseno", in considerazione di quanto costrittivo e scomodo possa essere un reggiseno. 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